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This section covers common questions about the dosage of Viagra. Across all trials, VIAGRA improved the erections of 43% of radical prostatectomy patients compared to 15% on placebo. One-third to one-half of the subjects in these studies reported successful intercourse at least once during a 4-week, treatment-free run-in period. There was no impairment of fertility in rats given sildenafil up to 60 mg/kg/day for 36 days to females and 102 days to males, a dose producing an AUC value of more than 25 times the human male AUC. In a study of healthy male volunteers, sildenafil (100 mg) did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates. In healthy male volunteers, there was no evidence of a clinically significant effect of azithromycin (500 mg daily for 3 days) on the systemic exposure of sildenafil or its major circulating metabolite.

Stop taking sildenafil and call your doctor or call 111 straight away if you have a sudden decrease or loss of vision. If Viagra is deemed safe for you, your Viagra dose will be adjusted based on response, i.e., whether your erectile dysfunction improved, and tolerance, i.e., if you had any side effects. If you are taking sildenafil for erectile dysfunction, you are unlikely to miss a dose since this medication is taken as needed, not on a regular dosing schedule. This medication is sometimes prescribed for other uses